Baisfu Top Quality Ranaconitine 98% Selling Well with Free Sample CAS No. 1360-76-5

Baisfu Top Quality Ranaconitine 98% Selling Well with Free Sample CAS No. 1360-76-5

Product Properties

Ranaconitine
CAS No.: 1360-76-5
20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-4,7,8,9-TETROL4-[2-(ACETYLAMINO)BENZOATE];
4-[2-(ACETYLAMINO)BENZOYLOXY]-20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-7,8,9-TRIOL; O4-(2-ACETAMIDOBENZOYL)RANACONINE;
(1ALPHA,14ALPHA,16BETA)-ACONITANE-4,7,8,9-TETROL20-ETHYL-1,14,16-TRIMETHOXY-4-[2-(ACETYLAMINO)BENZOATE];
7-HYDROXYLAPPACONITINE;

Product Name:Ranaconitine
Latin Name: Aconitum sinomontanum Nakai
Chemical Name: 20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-4,7,8,9-TETROL4-[2-(ACETYLAMINO)BENZOATE];
4-[2-(ACETYLAMINO)BENZOYLOXY]-20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-7,8,9-TRIOL; O4-(2-ACETAMIDOBENZOYL)RANACONINE;
(1ALPHA,14ALPHA,16BETA)-ACONITANE-4,7,8,9-TETROL20-ETHYL-1,14,16-TRIMETHOXY-4-[2-(ACETYLAMINO)BENZOATE];
7-HYDROXYLAPPACONITINE;
Appearance: Colorless needle crystal
CAS No.: 1360-76-5
MF: C32H44N2O9 MW: 600.705
Active Ingredient: Ranaconitine
Source: The root of the herbaceous plant, Aconitum sinomontanum Nakai, belongs to diterpenoid alkaloid
Detection Method: HPLC/UV
Purity:≥ 98% Density?1.39
Melting Point: 132-134?
Water Solubility: Insoluble in water, soluble in ethanol, Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetoneetc?etc.
Shelf Life: 2 Years

Packing & Delivery

Package: 1kg per bag with double plastic inside and aluminium foil bag outside, or 25kg per fibre drum with double plastic bag inside, or according to customers' requirement.
Storage: Store in cool & dry place. Keep away from strong light and heat.

Delivery: 1-2 working days after payment/FedEx, DHL, TNT, EMS, etc.

Detailed Description

Ranaconitine
CAS No.: 1360-76-5
20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-4,7,8,9-TETROL4-[2-(ACETYLAMINO)BENZOATE];
4-[2-(ACETYLAMINO)BENZOYLOXY]-20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-7,8,9-TRIOL; O4-(2-ACETAMIDOBENZOYL)RANACONINE;
(1ALPHA,14ALPHA,16BETA)-ACONITANE-4,7,8,9-TETROL20-ETHYL-1,14,16-TRIMETHOXY-4-[2-(ACETYLAMINO)BENZOATE];
7-HYDROXYLAPPACONITINE;

Aconitum leucostomum Worosch is a traditional Chinese medicine (TCM) and has a broad spectrum of health effects, but with a narrow therapeutic window. It is important to identify both the therapeutic ingredients and the toxic components to better utilize this TCM. The present study investigated the cardiotoxicity of the selected compounds in Aconitum leucostomum Worosch. The effects of extract of A. leucostomum Worosch and the isolated compounds on cardiocardiomyocytes were evaluated in vitro. Five known compounds in this TCM, including three C18-diterpene alkaloids, lappaconitine , N-deacetyllappaconitine , and Ranaconitine , and two C19-diterpene alkaloids, delvestidine and anthranoyllycoctonine, were isolated from A. leucostomum Worosch. The cardiotoxicity of these components and extract fractions, as measured by lactate dehydrogenase release and apoptosis, was ranked as follows, in descending order: delvestidine>anthranoyllycoctonine>pH 4 fraction>pH 8 fraction>aconitine>N-deacetyllappaconitine>Ranaconitine>lappaconitine. The cytotoxicity of these compounds was shown to be dose-dependent, with delvestidine and anthranoyllycoctonine being the two most toxic compounds to cardiomyocytes in our assays. These results provide a basis for future rational use of this TCM, reducing side effects while retaining therapeutic effects.

Functions

Ranaconitine
CAS No.: 1360-76-5
20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-4,7,8,9-TETROL4-[2-(ACETYLAMINO)BENZOATE];
4-[2-(ACETYLAMINO)BENZOYLOXY]-20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-7,8,9-TRIOL; O4-(2-ACETAMIDOBENZOYL)RANACONINE;
(1ALPHA,14ALPHA,16BETA)-ACONITANE-4,7,8,9-TETROL20-ETHYL-1,14,16-TRIMETHOXY-4-[2-(ACETYLAMINO)BENZOATE];
7-HYDROXYLAPPACONITINE;

1. Against HBV & HCV, can treat chronic hepatitis;
2. Anti cancer;
3. Can be used as pesticide;
4. Against pathogen;
5. Anti-allergy and anti-inflammation. it can regulate immunity and increase white blood cell.

Aconitum leucostomum Worosch is a traditional Chinese medicine (TCM) and has a broad spectrum of health effects, but with a narrow therapeutic window. It is important to identify both the therapeutic ingredients and the toxic components to better utilize this TCM. The present study investigated the cardiotoxicity of the selected compounds in Aconitum leucostomum Worosch. The effects of extract of A. leucostomum Worosch and the isolated compounds on cardiocardiomyocytes were evaluated in vitro. Five known compounds in this TCM, including three C18-diterpene alkaloids, lappaconitine , N-deacetyllappaconitine , and Ranaconitine , and two C19-diterpene alkaloids, delvestidine and anthranoyllycoctonine, were isolated from A. leucostomum Worosch. The cardiotoxicity of these components and extract fractions, as measured by lactate dehydrogenase release and apoptosis, was ranked as follows, in descending order: delvestidine>anthranoyllycoctonine>pH 4 fraction>pH 8 fraction>aconitine>N-deacetyllappaconitine>Ranaconitine>lappaconitine. The cytotoxicity of these compounds was shown to be dose-dependent, with delvestidine and anthranoyllycoctonine being the two most toxic compounds to cardiomyocytes in our assays. These results provide a basis for future rational use of this TCM, reducing side effects while retaining therapeutic effects.

Applications

Ranaconitine
CAS No.: 1360-76-5
20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-4,7,8,9-TETROL4-[2-(ACETYLAMINO)BENZOATE];
4-[2-(ACETYLAMINO)BENZOYLOXY]-20-ETHYL-1α,14α,16β-TRIMETHOXYACONITANE-7,8,9-TRIOL; O4-(2-ACETAMIDOBENZOYL)RANACONINE;
(1ALPHA,14ALPHA,16BETA)-ACONITANE-4,7,8,9-TETROL20-ETHYL-1,14,16-TRIMETHOXY-4-[2-(ACETYLAMINO)BENZOATE];
7-HYDROXYLAPPACONITINE;

1. Applied in agriculture field, as a natural plant pesticides that once touched the drug will suffocate;
2. Applied in pharmaceutical field, matrine injection on the treatment of chronic persistent hepatitis have a good effect; can treat trichomonas vaginitis
3. Applied in cosmetic field, it has good effect of anti-acne.

(1) Pharmaceutical as capsules or pills;
(2) Functional food as capsules or pills;
(3) Water-soluble beverages;
(4) Health products as capsules or pills.

Aconitum leucostomum Worosch is a traditional Chinese medicine (TCM) and has a broad spectrum of health effects, but with a narrow therapeutic window. It is important to identify both the therapeutic ingredients and the toxic components to better utilize this TCM. The present study investigated the cardiotoxicity of the selected compounds in Aconitum leucostomum Worosch. The effects of extract of A. leucostomum Worosch and the isolated compounds on cardiocardiomyocytes were evaluated in vitro. Five known compounds in this TCM, including three C18-diterpene alkaloids, lappaconitine , N-deacetyllappaconitine , and Ranaconitine , and two C19-diterpene alkaloids, delvestidine and anthranoyllycoctonine, were isolated from A. leucostomum Worosch. The cardiotoxicity of these components and extract fractions, as measured by lactate dehydrogenase release and apoptosis, was ranked as follows, in descending order: delvestidine>anthranoyllycoctonine>pH 4 fraction>pH 8 fraction>aconitine>N-deacetyllappaconitine>Ranaconitine>lappaconitine. The cytotoxicity of these compounds was shown to be dose-dependent, with delvestidine and anthranoyllycoctonine being the two most toxic compounds to cardiomyocytes in our assays. These results provide a basis for future rational use of this TCM, reducing side effects while retaining therapeutic effects.

Company Profile

Shaanxi Baisfu Biological Engineering Co., LTD. was founded in 2008, is a technological export-oriented private enterprise with the Rights of Self-Managed Import and Export, specializing in active ingredients modernized and industrialization research, development, production, and sales of natural medical botany.

Our factory covers an area of 6,000 square meters equipped with advanced equipment and the production process is in accordance with FDA.

Since its inception, the company is aiming at providing every customer with top best quality products and superior service at a reasonable and competitive price, all the time. And in the past 9 years, we’ve gained great progress.

Our products are exported to countries all over the world: USA, countries in North America, South America, European countries like UK, Germany, Sweden, Greece, Finland, Norway, France, Italy, Russia, Ukraine, Estonia, Spain, Latvia, etc. Asia countries like Malaysia, Indonesia, South Korea, Thailand, Philippines, Vietnam, Singapore, etc. Our products are selling very well in these areas. And other countries like Australia, Mexico, Salvatore, Costa Rica, and so on. What’s more, for the high quality products and superior service we provide, we’ve been highly appreciated by our customers. We are getting more and more returning customer day by day.


& Our Company always persist in:

Top Quality Products, Excellent Professional Knowledge, Superior Service

How to Order

1. Make sure your quantity need and Leave us message, with your mailed details shown: Including contact name, address information, contact phone, etc.
2. We send you a PI (Proforma Invoice) for price and payment detail.
3. Payment by Paypal or Western Union or T/T.
4. We arrange the delivery and update you the tracking number in time.

FAQ

Q1: Could you provide free sample for test?
A1: We can provide you free sample for test, and you only need to pay the delivery cost.

Q2: Which payment terms do you accept?
A2: PayPal, T/T, West Union, Bank Transfer, etc.

Q3: What's about the MOQ ?
A3: It depends on different products. Usually our MOQ is 5kg.

Q4: What’s the delivery lead time?
A4: We will make delivery within 1-2 days after receiving payment.

Q5: What about the delivery port?
A5: Main ports in China are available(Hongkong, Shenzhen, Guangzhou).